Game Locks Up ... Solid

This has been an on-going issue for me, for several months. Some days, I can get by with no crashes. Other days, I experience 6-7 crashes. It seems to happen mostly in towns when moving.

When moving through a town, if I move close to a house, there is a momentary freeze (everything stops in the game), as (I'm assuming) assets are instantiated and placed inside and around the house. Every once in a while, that will lock everything up, requiring a hard reboot of my machine.

Other instances where I sometimes notice a crash is when opening/scrolling through inventories (either my character's inventory, a store inventory, a Town Crier Lot list, bank inventory, etc).

No error logs are generated, as my entire computer locks up, with no way to escape. It requires me to power down the machine, and restart.

My drivers are all up to date.

Computer Stats:
MSI GT72 Dominator Pro-444
Intel Core i7 4980HQ (2.80 GHz)
NVIDIA GeForce GTX 980M
32 GB Memory
1TB SSD / 1TB HDD
Windows 10 64-Bit