I cannot enchant the Aether orb. I can place all items in alchemy screen and the click the button but it generates an error message on the screen. All the items mandrake, orb and gold disappear. If I relog everything reappears in my inventory. Tried several times always the same result.
You should submit a bug report. You can type /bug in game which will open the right forum section and you will have a passable format to provide the required information!
please don't bug again, add to the existing one if you have further information. https://www.shroudoftheavatar.com/forum/index.php?threads/aether-orb-cannot-be-enchanted.161700/